Yes, the whole purpose of punctuation is to point the sense. Same route as 'punctilious', meaning neat and exact. If it disambiguates and doesn't confuse, go with it. But with most common abbreviations it's not really necessary.
(Personally I think bi's is horribly ugly and I'd avoid using the abbreviation in that case as it's only a matter of a few letters to spell it out. Though even that triggers my 'person first, characteristic second' rule, also known as 'how not to sound like a Daily Mail headline writer.")
(My, that was a grotesque yet totally correct string of punctuation at the end of that last parenthesis.)
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Re: A bit of dissent
(Personally I think bi's is horribly ugly and I'd avoid using the abbreviation in that case as it's only a matter of a few letters to spell it out. Though even that triggers my 'person first, characteristic second' rule, also known as 'how not to sound like a Daily Mail headline writer.")
(My, that was a grotesque yet totally correct string of punctuation at the end of that last parenthesis.)